The Relation Between Hypertension And Age With Breast Cancer Incidence Rates In RSUD Dr. H. Abdul Moeloek Hospital Of Bandar Lampung In 2018


  • Mohamad Reihansyah Deswindra
  • Muhartono
  • Rizki Hanriko
  • Waluyo Rudiyanto



Age, breast cancer, hypertension


Breast cancer is one of the most highest incidence rate cancer in all countries. Age and Hypertension is known as risk factor for breast cancer. The purpose of this study is to know the relation between hypertension and age with breast cancer incidence rates in Dr. H. Abdul Moeloek Bandar Lampung. The method of this study is observational analytic study with case control design. The data that used are secondary data that gathered from medical records of patients in Dr. H. Abdul Moeloek Hospital and taken with consecutive sampling method. The data is analyzed using univariate and bivariate analysis using Chi-square test and Fisher test. The result is in the case group, hypertension percentage obtained was 12.5% ​​while those whose has not hypertension was 87.5%. In the control group the percentage of hypertension was 8.3% while those whose has not hypertension was 91.7%. In the case group ≥50 years of age percentage obtained was 54.2% while at age <50 years was 45.8%. In the control group ≥50 years of age percentage of 16.7% while at age <50 years at 83.3%. The results showed that age ≥50 years have a p value = 0,007 with OR = 5,909 and hypertension group have a p value = 0.500. The conclusion of this study is, there is no the relationship between hypertension and breast cancer incidence rates Lampung and there is relationship between the age of patients with breast cancer incidence rates in the Hospital of Dr. H. Abdul Moeloek Bandar Lampung.


Mahdiana R. 2010. Mencegah penyakit kronik sejak dini. Yogyakarta: Tora Book.

Sjamsuhidayat R, de Jong W. 2017. Buku ajar ilmu bedah, sistem organ dan tindak bedahnya. Edisi ke-4. Jakarta: EGC.

Rinaldis E, Tutt A, Dontu G. 2011. Breast cancer facts and figures 2015-2016. Breast Pathology. 1(1):352–9.

Kemenkes RI. 2016. Kanker payudara. Jakarta: Pusat Data dan Informasi Kementrian Kesehatan RI.

Utami V, Muhartono, Fiana DN, Soleha TU. 2014. Characteristic of carcinoma mammae at RSUD dr. H. Abdul Moeloek Bandar Lampung 2010-2012. J Agromed Unila. 1(1):1–7.

Pereira A, Garmendia ML, Alvarado ME, Albala CA. 2012. Hypertension and the risk of breast cancer in chilean women: A case-control study. 13(11):5829–34.

Han H, Guo W, Shi Wentao, Yu Y, Zhang, Y, Ye, X, et al. 2017. Hypertension and breast cancer risk: A systematic review and meta-analysis. Scientific Reports. Nature Publishing Group. 7(1):1–9.

Brown NS, Bicknell R. 2001. Hypoxia and oxidative stress in breast cancer Oxidative stress : its effects on the growth, metastatic potential and response to therapy of breast cancer. Breast Cancer Res. 3(5):323–7

Kang DH. 2002. Oxidative stress, DNA damage, and breast cancer. AACN. 13(4):540–9.

Virdis A, Duranti E, Taddei S. 2011. Oxidative stress and vascular damage in hypertension : role of angiotensin II. International Journal of Hypertension. 1(1):1–7

Stocks T, Van Hamelrijck M, Manjer J, Bjorge T, Ulmer H, Hallmans G, et al. 2012. Blood pressure and risk of cancer incidence and mortality in the metabolic syndome and cancer project. Hypertension AHA. 59(4):802–10.

Porto LAM, Lora KJB, Soares JCM, Costa LO. 2011. Metabolic syndrome is an independent risk factor for breast cancer. Arch Gynecol Obstet. 284:1271–6.

Siiteri, P. K. 1987. Adipose tissue as a source of hormones. e American journal of clinical nutrition. 1(45):277–82.

Rianti E, Tirtawati GA, Novita H. 2012. Faktor-faktor yang berhubungan dengan risiko kanker payudara. Jurnal Health Quality. 3(1):10–23.

Kaminska M, Ciszewski T, Szatan KL, Miolta P, Staroslawska E. 2015. Breast cancer risk factor. Prz Menopauzalny. 14(3):196–202.

Sihombing M, Sapardin AN. 2014. Faktor risiko tumor payudara pada perempuan umur 25-65 tahun di lima kelurahan kecamatan Bogor Tengah. Jurnal Kesehatan Reproduksi. 5(3):1–10.

Ban KA, Godellas CV. 2014. Epidemiology of breast cancer. Surg Oncol Clin N Am. 23(1):409–22.

Laamiri FZ, Bouyad A, Hasswane N, Ahid S, Mrabet M, Amina B. 2015. Risk factors for breast cancer of different age groups: Moroccan data. Open Journal of Obstetric an Gynecology. 5(1):79–87.



How to Cite

Deswindra, M. R. ., Muhartono, Rizki Hanriko, & Waluyo Rudiyanto. (2020). The Relation Between Hypertension And Age With Breast Cancer Incidence Rates In RSUD Dr. H. Abdul Moeloek Hospital Of Bandar Lampung In 2018. Medical Profession Journal of Lampung, 10(1), 11-15.




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