The Relationship Between Kidney Disorders and Mortality in COVID-19 Inpatients at Dr. H. Abdul Moeloek Hospital, Lampung
DOI:
https://doi.org/10.53089/medula.v16i1.1734Keywords:
Covid-19, kidney disorders, mortalityAbstract
Coronavirus Disease 2019 (Covid-19) is an infectious disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The risk of death from Covid-19 is reported to be higher due to kidney damage which causes various complications in patients. The background of this research was to determine the relationship between kidney disorders and the mortality rate of inpatients with Covid-19 at RSUD Dr. H. Abdul Moeloek, Lampung. This type of research is a retrospective analytic descriptive with a cross sectional approach, conducted from November to December 2022 at the Abdul Moeloek Hospital in Bandar Lampung. The population in this study were patients diagnosed with Covid-19 who were recorded as inpatients at RSUD Dr. H. Abdul Moeloek with a total of 361 samples selected according to the inclusion and exclusion criteria. The analytical test in this study used the Chi square test. Based on research, the majority of Covid-19 patients were female, aged 19- 59 years, with length of stay <14 days. The mortality rate for Covid-19 patients with comorbid kidney disorders is 54%. The results of the Chi Square test for the relationship between kidney impairment and mortality in Covid-19 hospitalized patients showed a p-value of 0.000. There is a relationship between kidney disorders and the death rate of Covid-19 inpatients at Dr. H. Abdul Moeloek Lampung Province. Hospitalized patients with comorbid CKD are more at risk of dying compared to Covid-19 patients without CKD.
References
World Health Organization. 2020. Coronavirus Disease 2019 (COVID-19) Situation Report. WHO. (ifac-papersonline). 19(1). 4477–4483.
Kementrian Kesehatan Republik Indonesia. 2020. Pedoman Pencegahan dan Pengendalian Coronavirus Disease (COVID-19).
Zhou P, Yang XL, Wang XG, et al. 2020.
A Pneumonia Outbreak Associated With A New Coronavirus of Probable Bat Origin.
Nature. 579(7798): 270–273.
Guan WJ, Ni ZY, Hu Y, et al. 2020. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 382(18): 1708–1720.
Pan XW, Xu D, Zhang H, et al. 2020. Identification of a Potential Mechanism of Acute Kidney Injury During the COVID-19 Outbreak: A Study Based on Single-Cell Transcriptome Analysis.
Intensive Care Med. 46(6): 1114–1116.
Ronco C, Reis T. 2020. Kidney Involvement in COVID-19 and Rationale for Extracorporeal Therapies. Nat Rev Nephrol. 16(6): 308–310.
Cheng Y, Luo R, Wang K, et al. 2020.
Kidney Disease is Associated With In-Hospital Death of Patients with COVID-19.
Kidney Int. 97(5): 829–838.
Malha L, Mueller FB, Pecker MS, et al. 2020. COVID-19 and Kidney Disease: Lost in Translation. Kidney Int. 98(2): 294–295.
Hirsch JS, Ng JH, Ross DW, et al. 2020.
Acute Kidney Injury in Patients Hospitalized With COVID-19. Kidney Int. 98(1): 209–218.
Rubin S, Orieux A, Prevel R, et al. 2020.
Characterization of Kidney Involvement in COVID-19 ICU Patients. Clin Med. 20(6): e218–e219.
Kementerian Kesehatan Republik Indonesia. 2021. Profil Kesehatan Indonesia 2021.
Oweis AO, Al-Rawashdeh MO, Al-Nassour EM, et al. 2022. Acute Kidney Injury Among Hospitalized Patients With COVID-19: Incidence, Predictors, and Outcomes. J Clin Med. 11(3): 1–10.
Appelman J, Liebst LS, Lindegaard MR. 2022. How Common Are High-Risk Coronavirus Contacts? A Video-Observational Analysis of Outdoor Public Place Behavior During The COVID-19 Pandemic. PLoS ONE. 17(3): 1–7.
Li Z, Wu M, Yao J, et al. 2021.
Caution on Kidney Dysfunctions of COVID-19 Patients. Front Med. 15(2): 254–259.
Borreli S, Provenzano M, Gagliardi I, et al. 2020. Sodium Intake and Chronic Kidney Disease. Int J Mol Sci. 21(13): 1–13.
Hunter RW, Bailey MA. 2019. Hyperkalemia: Pathophysiology, Risks and Management.Clin Med. 19(4): 359–365.
Kim GH. 2021. Acid–Base Balance in Chronic Kidney Disease. Electrolyte Blood Press. 19(1): 1–6.
Yong KC, Wijewickrama ES, Bandara HM, et al. 2022. Kidney Injury and Mortality in COVID-19 Patients: A Systematic Review. J Clin Med. 11(10): 1–12.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Medical Profession Journal of Lampung

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.











