The Association Between Age, Gender, and Occupation With Anemia in Pulmonary Tuberculosis Patients at RSUD Dr. H. Abdul Moeloek Lampung Period of January - December 2022

Authors

  • Ridha Riano Fathunnisa Medical Faculty, Lampung University
  • Putu Ristyaning Ayu Sangging
  • Winda Trijayanthi Utami
  • Tri Umiana Soleha

DOI:

https://doi.org/10.53089/medula.v16i1.1754

Keywords:

Anemia, Jenis Kelamin, Tuberkulosis Paru, Usia

Abstract

Pulmonary tuberculosis is an infectious disease caused by Mycobacterium tuberculosis and is classified as a chronic multisystem infection with diverse clinical manifestations. Hematological abnormalities are frequently observed in tuberculosis patients and are generally associated with non-immunological mechanisms. Anemia is one of the most common abnormalities. All chronic infections, including tuberculosis, can induce anemia through various pathogenic pathways. However, most studies indicate that suppression of erythropoiesis mediated by inflammatory factors plays a major role in the development of anemia in tuberculosis patients. This study aimed to describe the characteristics of anemia and identify factors associated with its occurrence in patients with pulmonary tuberculosis. An observational analytic study with a cross-sectional design was conducted. Data were obtained from the medical records of pulmonary tuberculosis patients with anemia at the Medical Records Unit of RSUD Dr. H. Abdul Moeloek Bandar Lampung from January to December 2022. A total of 85 patients who met the inclusion criteria were included and analyzed using univariate and bivariate analyses with the Chi-Square test. Univariate analysis showed that most patients had normocytic normochromic anemia, accounting for 66 patients or 77.6%, while microcytic hypochromic anemia was observed in 19 patients or 22.4%. Anemia was more common in male patients, with a proportion of 74.1%. Bivariate analysis demonstrated a significant association between age and anemia occurrence, with a p value of 0.024. No significant association was found between occupation and anemia or between sex and anemia. This study concludes that age is the only factor associated with anemia among pulmonary tuberculosis patients at RSUD Dr. H. Abdul Moeloek Bandar Lampung.

Author Biographies

Ridha Riano Fathunnisa, Medical Faculty, Lampung University

 

 

Putu Ristyaning Ayu Sangging

 

 

Winda Trijayanthi Utami

 

 

Tri Umiana Soleha

 

 

References

Kementerian Kesehatan Republik Indonesia. Infodatin Tuberkulosis 2018. Jakarta: Kemenkes RI; 2018. Available from: http://www.depkes.go.id/download.php?file=download/pusdatin/infodatin/infodatin%20tuberkulosis%202018.pdf

Kementerian Kesehatan Republik Indonesia. Pedoman Nasional Pelayanan Kedokteran: Tata Laksana Tuberkulosis. Jakarta: Kemenkes RI; 2020. Available from: https://www.tbindonesia.or.id/wp-content/uploads/2021/06/UMUM_PNPK_revisi.pdf

World Health Organization. Global tuberculosis report 2015. Geneva: WHO; 2015. Available from: https://www.who.int/tb/publications/global_report/en/

World Health Organization. Global tuberculosis report 2018. Geneva: WHO; 2018. Available from: https://www.who.int/publications/i/item/9789241565646

Dinas Kesehatan Provinsi Lampung. Profil Kesehatan Provinsi Lampung Tahun 2019. Bandar Lampung: Dinas Kesehatan Provinsi Lampung; 2019. Available from: https://dinkes.lampungprov.go.id/download/profil-kesehatan-provinsi-lampung-2019/

Pangaribuan L, Kristina, Perwitasari D, Tejayanti T, Lolong DB. Faktor-faktor yang mempengaruhi kejadian tuberkulosis pada umur 15 tahun ke atas di Indonesia. Buletin Penelitian Sistem Kesehatan. 2020;23(1):10–17. doi:10.22435/hsr.v23i1.2594

Maulidiyanti ETS. Status kadar hemoglobin dan jenis leukosit pada pasien TB paru di Surabaya. The Journal of Muhammadiyah Medical. 2020;3(1):53-60.

Dasaradhan T, Koneti J, Kalluru R, Gadde S. Tuberculosis-associated anemia: a narrative review. Cureus. 2022;14(8):1-8. doi:10.7759/cureus.27746

Kumar SB, Arnipalli SR, Mehta P, Carrau S, Ziouzenkova O. Iron deficiency anemia: efficacy and limitations of nutritional and comprehensive mitigation strategies. Nutrients. 2022;14:2976. doi:10.3390/nu14142976.

Acharya Y, Yang D, Jones AD. Livestock ownership and anaemia in Sub-Saharan African households. Public Health Nutr. 2021;24(12):3698–3709. doi:10.1017/S1368980020002827.

Vinantika L, Solikhah S. Anemia pada pasien rawat inap di Rumah Sakit Paru Respira, Yogyakarta. Berita Kedokteran Masyarakat. 2018;34(11):1-6.

Winardi S. Karakteristik anemia pada penderita tuberkulosis paru di RSUP Dr. Wahidin Sudirohusodo Makassar tahun 2018 [skripsi]. Makassar: Fakultas Kedokteran Universitas Hasanuddin; 2019.

Bukhari A, Hamid F, Minhajat R, Sutisna NS, Marsella CP. Non-nutritional and disease-related anemia in Indonesia: a systematic review. Asia Pacific Journal of Clinical Nutrition. 2020;29(1):41–54.

Suega K. Aspek biologik dan klinik dari besi: dari anemia defisiensi besi sampai anemia dengan kelebihan besi. Bali: PT Percetakan Bali; 2015.

World Health Organization. Global tuberculosis report 2022. Geneva: WHO; 2022. Available from: https://www.who.int/teams/global-programme-on-tuberculosis-and-lung-health/tb-reports/global-tuberculosis-report-2022

Tay MRJ, Ong YY. Prevalence and risk factors of anaemia in older hospitalised patients. Proceedings of Singapore Healthcare. 2011;20(2):71–9. doi:10.1177/201010581102000202.

Dewi RA. Pengalaman keberhasilan pengobatan pasien dengan tuberkulosis [skripsi]. Malang: Universitas Muhammadiyah Malang; 2022.

Mukherjee A, Kaeley N, Dhar M, Kumar S, Bhushan B. Prevalence, characteristics, and predictors of tuberculosis associated anemia. Journal of Family Medicine and Primary Care. 2019;8(7):2445–9.

Ng A, Tam WW, Zhang MW, Ho CS, Husain SF, McIntyre RS, Ho RC. IL-1β, IL-6, TNF-α and CRP in elderly patients with depression or Alzheimer’s disease: systematic review and meta-analysis. Scientific Reports. 2018;8(1):1–12. doi:10.1038/s41598-018-30487-6.

Akchurin O, Patino E, Dalal V, Meza K, Bhatia D, Brovender S, et al. Interleukin-6 contributes to the development of anemia in juvenile CKD. Kidney International Reports. 2019;4(3):470–83. doi:10.1016/j.ekir.2018.12.006.

Roy CN, Snyder PJ, Stephens-Shields AJ, Artz AS, Bhasin S, Cohen HJ, et al. Association of testosterone levels with anemia in older men. JAMA Internal Medicine. 2017;177(4):480–90. doi:10.1001/jamainternmed.2016.9540.

Lanser L, Fuchs D, Kurz K, Weiss G. Physiology and inflammation driven pathophysiology of iron homeostasis—mechanistic insights into anemia of inflammation and its treatment. Nutrients. 2021;13(11):1–29. doi:10.3390/nu13113732.

Agravat AH, Pujara K, Kothari RK, Dhruva GA. A clinico-pathological study of geriatric anemias. Aging Medicine. 2021;4(2):128–34. doi:10.1002/agm2.12150.

Unawekla JV, Moeis ES, Langi YA. Hubungan antara status gizi dan sistem imun seluler pada subyek penyakit ginjal kronik stadium V hemodialisis di Instalasi Tindakan Hemodialisis RSUP Prof. Dr. R. D. Kandou Manado. E-CliniC. 2018;6(1):1–6. doi:10.35790/ecl.6.1.2018.18682.

Gunadi VI, Mewo YM, Tiho M. Gambaran kadar hemoglobin pada pekerja bangunan. Jurnal e-Biomedik. 2016;4(2):2–7.

Heriyanto. Analisis aktivitas fisik ringan dan berat terhadap kadar hemoglobin. Jurnal Kesehatan Saelmakers Perdana. 2022;5(1):211–16. doi:10.32524/jksp.v5i1.406.

Hsieh NH, Chung SH, Chen SC, Chen WY, Cheng YH, Lin YJ, et al. Anemia risk in relation to lead exposure in lead-related manufacturing. BMC Public Health. 2017;17:389.

Published

2025-12-17

How to Cite

Fathunnisa, R. R. ., Sangging, P. R. A., Utami, W. T., & Soleha, T. U. (2025). The Association Between Age, Gender, and Occupation With Anemia in Pulmonary Tuberculosis Patients at RSUD Dr. H. Abdul Moeloek Lampung Period of January - December 2022. Medical Profession Journal of Lampung, 16(1), 103-109. https://doi.org/10.53089/medula.v16i1.1754

Issue

Section

Artikel

Most read articles by the same author(s)

<< < 1 2 3 4 5 6 7 > >>