The Anesthesia Management in Pregnant Women with Hyperthyroidism


  • Liana Sidharti Universitas Lampung



penyakit tiroid, hipertiroid, hormon tiroid, kehamilan


During pregnancy, there are changes in the structure and function of the thyroid gland and clinical conditions similar to excess thyroxine occur. These changes often make it difficult for clinicians to be able to distinguish whether the condition is a physiological condition or a thyroid disorder. The incidence of pregnancy with clinical symptoms of thyrotoxicosis and hyperthyroidism is 1 of 2000 pregnancies. Hyperthyroidism is a disorder that occurs when the thyroid gland produces more thyroid hormone than the body needs. Hyperthyroidism often occurs in reproductive age including during pregnancy. During pregnancy, thyroid hormone levels can be reduced or excessive, which can be bad for pregnant women and the fetus. Hyperthyroid conditions in pregnant women should be corrected wherever possible before pregnancy. Hyperthyroidism in pregnancy can provide serious complications, ranging from obstetric complications such as preeclampsia, maternal heart failure, premature birth and even fetal death. Hyperthyroidism in pregnancy often causes unspecific symptoms, so treatment should consider possible teratogenic drug effects.


Butterworth JF, Mackey DC, Wasnick JD. Morgan & Mikhail’s Clinical Anesthesiology 5th ed. Mc Graw Hill; 2013.

Yao FS. Anesthesiology Problem Oriented Patient Management 7th ed. Wolters Kluwer; 2010.

U.S. Department of Health and Service. Hyperthyroidism. National Endocrine and metabolism Service; 2010.

Sudoyo AW, Setiyohadi B, Alwi I, Simadibrata M, Setiadi S. Buku Ajar Ilmu Penyakit Dalam. Jakarta: InternaPublishing; 2009.

The Indonesian Society of Endocrinology Task Force on Thyroid Disease. Indonesian Clinical Practice Guidelines for Hyperthyroidisme. ASEAN Federation of Endocrine Societies. 2012: 27.

Nambiar V, Jagtap VS, Sarathi V, Lila AR, Kamalanathan S, Bandgar TR, et al. Prevalence and Impact of Thyroid Disorders on Maternal Outcome in Asian-Indian Pregnant Women. Department of Endocrinology, Seth G. S. Medical College. 2011

Kementerian Kesehatan RI. Riset Kesehatan Dasar 2013. Jakarta: 2013.

Cunningham FG, Leveno KJ, Bloom SL, Spong CY, Dashe JS, Hoffman BL, Casey BM, Sheffield JS. Williams Obstetrics 24th ed. New York:McGraw-Hill; 2014.

Kronenberg HM, Melmed S, olonsky KS, Larsen PR. Williams Textbook of Endocrinology. 11th ed. Philadelphia: 2008.

Chang DLF dan Pearce EN. Screening for Maternal Thyroid Dysfunction in Pregnancy: A Review of the Clinical Evidence and Current Guidelines. USA; 2012.

Douglas G, Nicol F, Robertson C. Macleod’s Clinical Examination 12th ed. China: Churchill Livingstone; 2009.

Batra CM: Fetal and Neonatal Thyrotoxicosis. Indian Journal of Endocr Metab 2013

Petersen KM, Solem EJ, Andersen JT, Petersen M, Brødbæk K, Køber K, et all. B-Blocker treatment during pregnancy and adverse pregnancy outcomes:a nationwide population-based cohort study. BMJ 2015.

Labadzhyan A, Brent AG, Hershman MJ, Leung MA. Thyrotoxicosis of Pregnancy. Journal of Clinical & Translational Endocrinology. 2014: 140-144.

Russel TW. Endocrine disease. In: Roberta LH, Catherine EL. Stoelting’s Anaesthesia & co-existing disease, 5th ed. Churchstill Livingstone Publications; 2008: 382-384.

Green AS, Abalovich M, et al : Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and Postpartum. Thyroid 2011 ; 20 : 1081-1128.

Groot LD Management of thyroid dysfunction during pregnancy and postpartum : an endocrine society clinical practice guideline. J Clin Endocrinol Metab. 2012; 97(8): 2543-2565.



How to Cite

Sidharti, L. (2023). The Anesthesia Management in Pregnant Women with Hyperthyroidism. Medical Profession Journal of Lampung, 13(4), 495-503.




Most read articles by the same author(s)