G4P3A0 in 30 Weeks With Imminent Preterm and Premature Rupture of Membrane


  • Putu A.L Amrita Kirana
  • Nurul Islamy
  • Ade Yonata




Imminent preterm, premature ruptur of membrane, treatment


Imminent preterm is the presence of a threat in pregnancy with emergence signs in 20 weeks-37 weeks. Preterm premature rupture of membrane is rupture of chorioamniotic membrane before the onset of childbirth and occurs in gestational age less than 37 weeks.. This study is a case report. A 34 years old woman with preterm pregnancy come with complained of the release of amniotic fluid that is odorless and can not be held from seven hours before entering hospital and accompanied by two days before entering hospital. It is accompanied by pain that intermitently radiating to the waist but still rare. From physical examination found moderate sick in general condition, compos mentis, BP 120/70mmHg, pulse 100 x/min, respiratory rate 20 x/min, temperature 36,6oC. General examination within normal limits. In obstetric examination found that fundus uteri is 3 finger  under proccesus xiphoideus (26 cm), his (+) 2x in 10 minutes duration 10-12 seconds, fetal heart rate 144 x/min. In inspekulo examination found that portio is livid, OUE closed, amniotic fluid (+) not active, erosion/laseration/polip (-), lakmus (+) red to blue. Vaginal toucher not performed in this patient. The diagnosis are G4P3A0 in 30 weeks pregnancy, not inpartu yet, with imminent preterm and premature rupture of membrane. Patient planned conservative therapy such as observation of his, fetal heart rate, and vital signs mother, IVFD RL gtt x x/min, dexamethasone 2x10 mg, nifedipine 4x10 mg, cefadroxil 2x500mg.


Nugroho T. Kasus emergency kebidanan. Yogyakarta: Nuha Medika; 2010

Manuaba, Ida Bagus Gede. Pengantar kuliah obstetric. Jakarta: EGC; 2007

Prawirohardjo S. Ilmu kebidanan. Jakarta: PT Bina Pustaka Sarwono Prawirohardjo; 2008

ACOG Committee on Practice Bulletin Obstetrics. ACOG Practice Bulletin no. 80: Premature rupture of membranes: Clinical guidelines for obstetrician-gynecologists. Obstet Gynecol. 2007; 109(4):1007-19

Cunningham FG, Norman FG, Kenneth JL, Larry CG III, Jhon CH, Katharine DW. Obstetri William. Jakarta: Penerbit Buku Kedokteran EGC;2005

Soewarto. S. Ketuban pecah dini. Dalam : Ilmu Kebidanan. Edisi ke-4. Jakarta: PT. Bina Pustaka Sarwono Prawirohardjo; 2011.Hlm. 678-82

Mohr T. Premature rupture of the membranse. Gynakol Geburtsmed Gynakol Endokrinol. 2010; 5(1): 28-36

Depkes. Profil Kesehatan Provinsi Lampung. Bandar Lampung: Depkes:2015

Wiknjosastro H. Ilmu Kebidanan. Edisi ke-4 Cetakan ke-2. Jakarta: Yayasan Bina Pustaka Sarwono Prawirohardjo, 2009; 523 - 529.

Stuart EL, Evans GS, Lin YS, Powers HJ. Reduced Collagen and Ascorbic Acid Concentrations and Increased Proteolytic Susceptibility with Prelabor Fetal Membrane Rupture in Women. Biol Reprod. 2005; 72(1): 230-5.

Gian CD. Good clinical practice advice: Prediction of preterm labor and preterm premature rupture of membranes. Wiley International Federation of Gynecology and Obstetrics. 2019

Davidson KM. Detection of premature rupture of the membranes. Clin Obstet Gynecol. 1991;34(4): 715-22

Lewis DF, Major CA, Towers CV, Asrat T, Harding JA, Garite TJ. Effects of digital vaginal examination on latency period in preterm premature rupture of membranes. Obstet Gynecol.1992; 80(4): 630–4

Alexander JM, Mercer BM, Miodovnik M, Thurnau GR, Goldenburg RL, Das AF et al. The impact of digital cervical examination on expectantly managed preterm rupture of membranes. Am J Obstet Gynecol.2000;183(4): 1003-7

Oxorn, H. Ilmu Kebidanan Patologi dan Fisiologi Persalinan (Human Labor and Birth). Yogyakarta: YEM; 2010.

Price, Sylvia A & Lorraine, M. Wilson. Patofisiologi : Konsep Klinis Proses-Proses Penyakit Edisi 6. Jakarta : EGC; 2005

Price, Sylvia A & Lorraine, M. Wilson. Patofisiologi : Konsep Klinis Proses-Proses Penyakit Edisi 6. Jakarta : EGC; 2005

Oktavia N, Yulistiani, Markus UH, Mamo HI. Effectiveness and safety differences of isoxsuprine and nifedipine ad tocolytics in the risk of preterm labor. Folia Medica Indosiana. 2017; 53(4) 242.



How to Cite

Putu A.L Amrita Kirana, Nurul Islamy, & Ade Yonata. (2020). G4P3A0 in 30 Weeks With Imminent Preterm and Premature Rupture of Membrane. Medical Profession Journal of Lampung, 10(3), 456-460. https://doi.org/10.53089/medula.v10i3.94