Obstructive Sleep Apnea (OSA) in Productive Age


  • Lyvia Annisarahma Fakultas Kedokteran Universitas Lampung
  • Nisa Karima
  • Putu Ristyaning Ayu Sangging
  • Waluyo Rudiyanto




Risk factors, obstructive sleep apnea (OSA), productive age


Obstructive sleep apnea (OSA) is a sleep disorder which characterized by cessation of breathing for more than 10 seconds. A blockage in the upper respiratory tract may be the cause of OSA. One known risk factor for OSA is smoking. Moreover, the degree of physical activity might also influence OSA risk. This article is a literature review with a variety of the latest sources that are relevant to the topic. The sources used were obtained from the search engine for health journals. The prevalence of OSA in the productive age community in Asia is 4.1 - 7.5%. Some factors that affect the symptoms of OSA, especially in productive age, namely obesity, male sex, old age, genetic, smoking habits, and small upper airway diameter. OSA is characterized by snoring, periodic apnea, hypoxemia during sleep and hypersomnolence during the day. Some symptoms of OSA are snoring hard and annoying, stopping repeated breathing during sleep at night, insomnia, fatigue, and drowsiness during the day. Death from OSA in productive age is usually caused by complications after having OSA in the long period ahead.

Author Biographies

Lyvia Annisarahma, Fakultas Kedokteran Universitas Lampung



Nisa Karima



Putu Ristyaning Ayu Sangging



Waluyo Rudiyanto




American National Heart Association. Sleep Apnea: Causes and Risk Factors [Internet]. Disitasi tanggal 27 September 2023. Tersedia dari https://www.nhlbi.nih.gov/health/sleep-apnea/causes

Arnardottir ES, Bjornsdottir E, Olafsdottir KA, Benediktsdottir B, Gislason T. Obstructive Sleep Apnoea in the General Population: Highly Prevalent but Minimal Symptoms. European Respiratory Journal. 2016; 47(1).

Bahagia W, Ayu PR. Sindrom Obstructive Sleep Apnea. Medula. 2020; 9(4).

Benjafield A, Valentine K, Ayas N, Eastwood PR, Heinzer RC, Ip MS, et al. Global Prevalence of Obstructive Sleep Apnea in Adults: Estimation Using Currently Available Data. Risk And Prevalence of Sleep Disordered Breathing. 2018.

Berry RB, Albertario CL, Harding SM., Lloyd RM, Plante DT, Quan SF, et al. The AASM Manual for the Scoring of Sleep and Associated Events. In Journal of Clinical Sleep Medicine. 2018; 2(5)

Cambron L, Roelants F, Deflandre E, Raskin S, Poirrier R. The Sleep Obstructive Apnea and Hypopnea Syndromes. Revue Medicale de Liege. 2004; 59(1): 19–28.

Chowdhuri S, Quan SF, Almeida F, Ayappa, I, Batool-Anwar S, Budhiraja R, et al. An Official American Thoracic Society Research Statement: Impact of Mild Obstructive Sleep Apnea in Adults. American Journal of Respiratory and Critical Care Medicine. 2016; 193(9).

Collop NA, Anderson WM, Boehlecke B, Claman D, Goldberg R, Gottlieb DJ, et al. Clinical Guidelines for The Use of Unattended Portable Monitors in The Diagnosis of Obstructive Sleep Apnea in Adult Patients. Journal of Clinical Sleep Medicine. 2007; 3(7)

da Silva RP, Martinez D, Bueno KS, Uribe-Ramos JM. Effects of Exercise on Sleep Symptoms in Patients with Severe Obstructive Sleep Apnea. Jornal Brasileiro de Pneumologia. 2019; 45(3).

Gottlieb DJ, Punjabi NM. Diagnosis and Management of Obstructive Sleep Apnea: A Review. JAMA - Journal of the American Medical Association. 2020; 323(14).

Hall JE, Hall ME. Guyton and Hall: Textbook of Medical Physiology 14th Edition. Elsevier. 2021.

Jonas DE, Amick HR, Feltner C, PalmieriWeber R, Arvanitis M, Stine A, et al. Screening for Obstructive Sleep Apnea in Adults Evidence Report and Systematic Review for the US Preventive Services Task Force. In JAMA - Journal of the American Medical Association. 2017; 317(4).

Kadarullah O, Annisa Y. Pengaruh Obstructive Sleep Apnea (OSA) terhadap Terjadinya Hipertensi di Poli Saraf RSUD Prof. Dr. Margono Soekarjo. SAINTEKS. 2016; 11(2):11-21.

Kamelia T. Obstructive Sleep Apnea: Panduan Tatalaksana Diagnostik dan Manajemen Terkini. Indonesia Journal Chest. 2022; 9(1).

Kim KS, Kim JH, Park SY, Won HR, Lee HJ, Yang HS, et al. Smoking Induces Oropharyngeal Narrowing and Increases the Severity of Obstructive Sleep Apnea Syndrome. Journal of Clinical Sleep Medicine. 2020; 8(4).

Koh WP, Wong HS, Poh Y, Mok Y. Prevalence and Predictors of Positional OSA in A Southeast Asian Population. Chest. 2019; 155(45).

Lam B, Lam DC. Ip MS. Obstructive Sleep Apnoea in Asia. International Journal of Tuberculosis and Lung Disease. 2007; 11(1).

Lin YN, Li QY, Zhang XJ. Interaction Between Smoking and Obstructive Sleep Apnea: Not Just Participants. Chinese Medical Journal. 2012; 125(17):3150-3156

Lyons MM, Bhatt NY, Pack AI, Magalang UJ. Global Burden of Sleep-Disordered Breathing and Its Implications. Respirology. 2020; 25(7).

Maeda T, Fukunaga K, Nagata H, Haraguchi M, Kikuchi E, Miyajima A, et al. Obstructive Sleep Apnea Syndrome Should Be Considered as a Cause of Nocturia in Younger Patients Without Other Voiding Symptoms. In Canadian Urological Association Journal. 2016; 10: 7–8.

Mirrakhimov AE, Sooronbaev T, Mirrakhimov EM. Prevalence of Obstructive Sleep Apnea in Asian Adults: A Systematic Review of The Literature. BMC Pulmonary Medicine. 2013; 13(1).

Park JG, Ramar K, Olson EJ. Updates on Definition, Consequences, and Management of Obstructive Sleep Apnea Concise Review for Clinicians. In Mayo Clinic Proceedings. 2011; 86(6).

Ryan CM, Bradley TD. Pathogenesis of Obstructive Sleep Apnea. In Journal of Applied Physiology. 2005; 99(6).

Shahid A, Wilkinson K, Marcu S, Shapiro CM. STOP, THAT and One Hundred Other Sleep Scales. STOP, THAT and One Hundred Other Sleep Scales. 2012.

Tan A, Cheung YY, Yin J, Lim WY, Tan LW, Lee CH. Prevalence of Sleep-Disordered Breathing in a Multiethnic Asian Population in Singapore: A Community-Based Study. Respirology. 2016; 21(5).

Young T, Skatrud J, Peppard PE. Risk Factors for Obstructive Sleep Apnea in Adults. JAMA. 2004; 291(16).



How to Cite

Annisarahma, L. ., Karima, N., Sangging, P. R. A., & Rudiyanto, W. (2024). Obstructive Sleep Apnea (OSA) in Productive Age. Medical Profession Journal of Lampung, 14(1), 143-149. https://doi.org/10.53089/medula.v14i1.951




Most read articles by the same author(s)

<< < 1 2 3 4